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Short Communication Open Access
A simple and sensitive spectrophotometric method for the determination of cefadroxil anhydrous and its dosage forms is described. The method is based on the reaction of the drug with Folin-Ciocalteu reagent in presence of sodium hydroxide and stannous chloride to form a blue coloured chromogen having Î»max at 970 nm. The absorbance was found to be linear with the concentration in the range of 5-25 Î¼g/10 ml. The colour developed was stable up to 5 h.
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Author(s): M V V Prasad R Nagaraju T V Narayana