alexa Abstract | Spectrophotometric determination of febendazole.

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access


A simple spectrophotometric method for the determination of febendazole by hydroxamic acid formation in dosage forms is described. Febendazole reacts with hydroxylamine hydrochloride in alkaline medium to give hydroxamic acid, which forms a reddish violet coloured complex with Iron (III) in acidic medium having maximum absorbance at 500 nm, molar absorptivity of 5.0 x 10 (3) 1.mol(-1) cm(-1).

Author(s): SP Chudasama

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