alexa Abstract | Spectrophotometric estimation of famciclovir in bulk and tablet dosage form

Indian Journal of Pharmaceutical Sciences
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Two, simple, accurate, rapid and sensitive methods have been developed for the estimation of famciclovir in tablet dosage forms. Method A is based on the nucleophillic substitution product with Folin's reagent to form colored chromogen exhibiting absorption maximum at 454 nm with apparent molar absorptivity of 3.99×10 4 l/ and obeyed Beer's law in the concentration range of 2-10 µg/ml. Method B is based on diazotisation and coupling reaction with resorcinol to form colored chromogen exhibiting absorbance maximum at 386 nm with apparent molar absorptivity of 3.15×10 4 l/ and obeyed Beer's law in the concentration range of 7-21 µg/ml.

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Author(s): S Nizamuddin BM Gurupadayya MC Ravi YN Manohara S Appala Raju

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