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Short Communication Open Access
A simple, accurate and economical spectrophotometric method was developed for simultaneous estimation of nimesulide and diclofenac sodium in bulk drug and in combined formulations using simultaneous equation method. Nimesulide and diclofenac sodium has Î»max at 297 nm and 283 nm respectively in methanol, showing linearity in the concentration range of 5-40 Î¼g/ml and 2.5- 25 Î¼g/ml respectively. The results of analysis have been validated statistically and recovery studies confirmed the accuracy of the proposed method.
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Author(s): KEV Nagoji M Kiran Kumar MEB Rao KV Kanna Rao