alexa Abstract | Study of epidemiology of HPV infection in the Uterine Cervix of Women's in Delhi /NCR regions, India

International Journal of Drug Development and Research
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Abstract

One of the most common cancers among Indian women is the cancer of cervix. Hence, the Present study is undertaken to determine the prevalence of HR-HPV DNA in women in Delhi / NCR regions. The significance of detection of HPV provides the base to be used as a tool to identify women, at the risk of subsequent development of cervical cancer. It is the utmost necessity to identify the prevalence of high risk- Human Papilloma Virus (HR-HPV) in the women with cervical cytology for early treatment. Total of 1931 samples (cervical samples) from different hospitals in Delhi / NCR regions of India were collected in between January 2006 to December 2009. The cervical cytobrush was used for collection of samples from cervix and then the samples were transported in virus transport media (Digene Diag, Md). Hybrid capture assay II (HCA II) for HPV DNA detection from Digene Diagnostics (Silver Spring, Md.) was used for the detection of High risk Human Papilloma Virus. High risk Human Papilloma Virus was detected in 232 cases (12.01%). As analyzed it was observed that positivity rate has increased for last few years, 9.49 %, 11.66 %, 11.94 %, 14.7 %, in the year 2006, 2007, 2008, and 2009 respectively.

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Author(s): Sharma Veena Singh Premraj Sharma Narotam Pracheta Paliwal Ritu

Keywords

Hybrid Capture Assay, Human Papilloma Virus, retinoblastoma.

 
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