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Research Paper Open Access
Ibuprofen dispersible tablets using Plantago ovata mucilage powder, Ocimum basilicum mucilage powder, Plantago ovata husk powder and Ocimum basilicum seed powder as disintegrants were prepared and disintegrating property was studied. The swelling index of the above disintegrants was studied. Disintegrating property of the above disintegrants were evaluated by comparing with the formulations of starch powder as standard disintegrant. The study revealed that Plantago ovata seed powder and mucilage powder were effective in low concentrations (5%) as disintegrants compared to others. The study further revealed a poor relation between the swelling Index and disintegrating efficiency.
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Author(s): K Srinivas K Prakash HR Kiran PM Prasad MEB Rao