alexa Abstract | Study of risk factors for metabolic syndrome in subjects from rural area of Kurnool district

Journal of Chemical and Pharmaceutical Research
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Abstract

The ongoing rapid urbanization of India offers rural population the opportunity not only of economic improvement but also substantial health risk. The non-communicable disease (NCD) risk in India is increasing proportionally with increased risk for metabolic syndrome (MetS). There is no published data on metabolic syndrome risk factors from rural population of Kurnool district. To assess the MetS risk factors among rural population of Kurnool district using modified NCEP ATP III criteria. We studied 344 individuals with the age range 20-60 years. The risk factors for MetS were considered on the basis of modified NCEP ATP III criteria was defined by modified NCEP ATP III criteria, determined in terms of age and sex. Other variables were evaluated by using simple logistic regression methods. A total 33.65% men and 29.49% women were at high risk for MetS. Increased WC (52.03%) and decreased HDL-C (73.83%) followed by hypertriglyceridemia (37.50%); hypertension (36.04%); and hyperglycemia (18.02%) are found to be the main culprits for MetS in this population. The other physiological and behavioural CVD risk factors are as follows smoking 23.83%, alcohol intake 27.03%, history of type 2 DM 13.27%, history of HTN 11.91%, family history of type 2 DM 11.91% and family history of hypertension 7.55%.. Based on BMI percentage of underweight subjects is 6.10%; overweight/obesity (BMI ≥25.0)-57.26% and only 34.88% subjects are with normal BMI. MetS is present in 21.27% of subjects with normal BMI. Cardiovascular risk index calculated by Castelli index I, II and non HDL/HDL-c have shown significant correlation (r=0.0625; 0.0575; 0.0578 respectively) with number of MetS risk factors. MetS is present in 36.11% sedentary life style subjects whereas it was 30.88% among the subjects doing normal to hard work life style. MetS risk factors were high among this population. Central obesity and decreased HDL-c are found to be major risk factors. This scenario needs a better appraisal in order to create awareness to prevent or reduce these modifiable MetS risk factors among this population.

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Author(s): Pandit Vinodh Bandela J G Ambekar Nilima N Dongre K Durga Prasad and B B Devaranavadagi

Keywords

Kurnool, Prevalence, Metabolic Syndrome (MetS), metabolic syndrome

 
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