alexa Abstract | Studying the effects aqueous extract of Urtica dioica and swimming training on the histochemical properties of liver in diabetic rats

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access


Urtica dioica (UD) has been used as antihypertensive, antihyperlipidemic, anti antioxidant and anti diabetic herbal medicine. The purpose of this study was to study the effect of the diabetic rats of a swimming workout session along with the use of aqueous extract of Urtica dioica on histochemical properties of liver in rats.In this experimental study, 54 male Wistar rats injected with streptozotocin after induced diabetes as to injected intraperitoneal were randomly divided into 9 groups including healthy control , diabetes control, metformin at a dose of 100(gavage), diabetes and swimming, metformin and swimming, diabetes and UD aqueous extract at a dose of 1.25, diabetes and UD aqueous extract at a dose of 0.625(gavage), diabetes and UD extract dose of 1.25 and swimming, diabetic and UD extract at dose of 0.625(mg/kg/day) and swim. Swim training protocol was performed for 4 weeks, 5 days per week. Blood Aspartate aminotransferase (AST), alkaline phosphatase (ALP), Alanine amino transferase (ALT) were determined. ALP levels in diabetic groups and swim training, metformin and swim training, diabetes and UD extract at a dose of 0.625 and diabetes with UD extract at a dose of 1.25 and swim training with diabetic control group had a significant decrease(p-value of the respectively 0.02, 0.03, 0.01, 0.02). ALT, AST and metformin levels compared to diabetic control group were not significantly different. The present results suggest that swim training with UD extract on liver index was dose-dependent and also has synergistic effects on the liver factors in rats with hyperglycemia.

To read the full article Peer-reviewed Article PDF image

Author(s): Masomeh Salmani Ali Aalizadeh Sara Moghimi Bahman Tarverdizadeh Samad Akbarzadeh Saeed Changizi Ashtiyani and Mohammad AliAzarbayjani


Urtica dioica, hyperglycemia, rats., histochemical properties, liver

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version