alexa Abstract | Sulfonamide derivative and maleic anhydride based transition metal complexes: As potent antimicrobial agents

Journal of Chemical and Pharmaceutical Research
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Original Articles Open Access

Abstract

In the present study a novel 4-oxo-4-((4-N-(thiazol-2-yl)sulfamoyl)phenyl)amino)but-2-enoic acid (OTSPAB) was prepared by reaction of maleic anhydride with Sulphathiazol. The prepared ligand was characterized by elemental analysis and spectral studies. The transition metal complexes viz. Cu2+, Ni2+, Co2+, Mn2+ and Zn2+ of OTSPAB were prepared and characterized by metal-ligand (M:L) ratio, IR, reflectance spectroscopies and magnetic properties. All the prepared metal complexes and ligand were studies as antimicrobial agent. Among all the metal complexes, Zn2+ and Cu2+ metal complexes have shown significant activity

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Author(s): Hitesh R Patel and Asha D Patel

Keywords

maleic anhydride, Sulphathiazol, Magnetic moment, Spectroscopic study and Antifungal properties, Sulfonamide

 
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