alexa Abstract | Synthesis And Antimicrobial Activity Of N1- (Arylidine Hydrazidomethyl)-Indoles, 2-(Substituted Aryl)-3-(N1-Indolyl Acetamidyl)-4-Oxo-Thiazolidines And 5-Benzylidine Derivatives Of Thiazolidinones

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Paper Open Access

Abstract

Several N1-(arylidine hydrazidomethyl)-indoles were prepared by condensing N1-indolyl acetyl hydrazine with different substituted benzaldehydes. 2-(substituted aryl)9-(N1-indolyl acetamidyl)- 4-oxo-thiazolidines were prepared by condensing N1-(arylidine hydrazidomethyl)-indoles with mercaptoacetic acid followed by the Knoevanagel condensation with benzaldehyde leading to the 5-benzylidine derivatives. The IR, 1HNMR and mass spectral studies confirmed the structures of these compounds. The synthesized compounds were tested in vitro against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi, Pseudomonas aeruginosa, Proteus vulgaris, Candida albicans and Aspergillus niger. The zones of inhibition were compared with the standard drugs under the identical conditions.

To read the full article Peer-reviewed Article PDF image

Author(s): V Lather PVR Chowdary

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords