alexa Abstract | Synthesis and antimicrobial activity of novel 2-Methyl-3-(1'3'4'-Thiadiazoyl)-4-(3h) Quinazolinones

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication Open Access


With a view to explore the versatile lead molecule 4(3H)-quinazolinones, a series of novel 2-methyl-3-(1'3'4'-thiadiazoyl)-4-(3H) quinazolinones have been synthesised by reacting 2-amino-5-aryl/alkyl-1'3'4'-thiadiazoyl with 2-substituted benzoxazin-2-one. The designed compounds (5a-f) were screened in vitro for antibacterial activity on Staphylococcus aureus , Bacillus subtilis , and Escherichia coli . Antifungal activity was screened against Candida albicans , Aspergillus niger , and Curvularia lunata . Synthesised compounds exhibited both antibacterial and antifungal activity.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Varsha Jatav SK Jain SK Kashaw P Mishra

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version