alexa Abstract | Synthesis and antimicrobial activity of some novel 2-amino thiazole derivatives

Journal of Chemical and Pharmaceutical Research
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A series of 2-aminothiazoles derivatives have been synthesized and tested for in vitro antibacterial and antifungal activity on different microorganisms. Syntheses have been carried out following simple methodology in excellent isolated yields. The structure and purity of the original compounds were confirmed by IR, NMR, and elemental analysis. All compounds were tested for antibacterial and antifungal activity against Bacillus subtilus (+ve), E. coli (-ve), albicans (+ve) and Aspergillus niger (-ve) on concentration of 50 and 100μg/ml by Diskdiffusion method. These preliminary results indicate that some of compounds are exhibiting good activity.

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Author(s): Narendra Singh Uma Shankar Sharma Niranjan Sutar Sushil Kumar and UmeshKumar Sharma


Thiazole, 2-Chloro-N-(thiazol-2-yl) acetamide, Antimicrobial activity.

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