alexa Abstract | Synthesis and biological activity studies of some thiazolidinones and azetidinones

Indian Journal of Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication Open Access


A series of 4-thiazolidinones and 2-azetidinones have been synthesized by condensation of 4,4'-diaminodiphenylsulphone with various aromatic or heterocyclic aldehydes to yield the Schiff's bases. Cyclocondensation of Schiff's bases with 2-mercaptopropionic acid afforded 4-thiazolidinone derivatives, and cyclocondensation of Schiff's bases with chloroacetylchloride in presence of triethylamine afforded 2-azetidinone derivatives. The structures of the newly synthesized compounds were confirmed by analytical and spectral (IR, NMR, and Mass) data. All these compounds were evaluated for their in vitro growth-inhibitory activity against several microbes. Compound 4b and 4c exhibited equipotent antibacterial activity with the reference standard ampicillin against Bacillus subtilis.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): PD Mehta N PS Sengar E VS Subrahmanyam D Satyanarayana

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version