alexa Abstract | Synthesis and biological evaluation of some novel quinazolones

Indian Journal of Pharmaceutical Sciences
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Abstract

In view of the potent antimicrobial and antiinflammatory activities exhibited by quinazolin-4-(3H)-ones, a series of novel 2, 3-disubstituted-3,1-quinazolin-4-(3H) ones have been synthesized. The synthesized compounds were screened for antibacterial and antiinflammatory activities. Compounds 3a and 3l showed significant antiinflammatory activity comparable to ibuprofen, while the compound 3J showed antibacterial activity comparable to ciprofloxacin.

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Author(s): EM Jessy A Thirugnana Sambanthan J Alex CH Sridevi KK Srinivasan

 
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