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Original Articles Open Access
Carvedilol is prepared by different synthetic approaches. One of the approach is the condensation of 4-(2, 3-epoxyprpoxy) carbazole with 2-(2-methoxyphenoxy) ethyl amine in monoglyme solvent. In this publication, impurities and their origin of formation during the synthesis of 4-(2, 3-epoxypropoxy) carbazole and 2-(2-methoxyphenoxy) ethyl amine is discussed. These impurities are synthesized and well characterized by spectral analysis.
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Author(s): K Suneel Kumar K Tatendra Reddy G Omprakash P K Dubey
Carvedilol, 4-(2, 3-Epoxyprpoxy) carbazole, 2-(2-Methoxyphenoxy) ethyl amine, Potential impurities, Spectral analysis, receptor, Carvedilol