alexa Abstract | Synthesis and characterization of Schiff base complexes of Cu[ll] and Co[ll]

Journal of Chemical and Pharmaceutical Research
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Original Articles Open Access

Abstract

The complexes [SGC, SGCO] of Cu [ll], and Co [ll] ions with a Schiff base [SG] derived from salicylaldehyde and sulfaguanidine have been investigated. The resulting complexes were characterized by UV/Vis IR, 1HNMR spectral studies, elemental analysis, molar conductance, XRD, Magnetic suceptibility and antimicrobial activity. The molar conductance measurement indicates that the complexes were non electrolytes. The IR data shows that complexes were mono basic ligand with NO bidentate sites. The XRD study shows that the complexes were microcrystalline in nature, the antimicrobial activity of the complexes were tested against the bacterial, E.coli, Pseudomonous aeroginosa, Staphylococcus aureus and fungi Candida by the Disc diffusion method. The complex shows stronger antimicrobial activity than the free ligands.

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Author(s): M Shyamala Devi Thankachi and S Suthakumari

Keywords

Schiff base, Sulfaguanidine, Antifungal and Antibacterial activities, Synthesis

 
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