alexa Abstract | Synthesis and characterization of some new pyrazolines derivatives and their biological activity

Journal of Chemical and Pharmaceutical Research
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Original Articles Open Access

Abstract

Six different hydrazine’s (hydrazine hydrate 80%, phenyl hydrazine, thiosemicarbazide, semicarbazide,2,4- dinitrophenyl hydrazine and 4- phenyl thiosemicarbazide ) were reacted with six different types of substituted chalcones α,β- unsaturated ketenes to yield pyrazole derivatives then characterized the products with infrared spectra, elemental analysis, mass spectra, 1H and 13C-NMR spectra. Finally their biological activity for some of the new pyrazoles were studied.

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Author(s): Khensaa S Saud Nezar L Shihabaldain and Ali A Shareef

Keywords

pyrazolines derivatives, biological activity

 
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