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Original Articles Open Access
A series of novel 1,3-thiazolidin-4-ones(2a-h) have been synthesiszed from isoxazolyl hydrazide-hydrazone derivatives(1a-h).These hydrazide-hydrazone derivatives undergoes cyclocondensation with mercaptoacetic acid in dioxane in the presence of anhydrous zinc chloride give title compounds in good yields(Table-I). Structure of all the synthesized compounds have been established on the basis of IR, 1HNMR and Mass spectral data.
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Author(s): Ramu Kakkerla K Ramamurthy M P S Murali Krishna and Nerella Ashok
Isoxazolyl hydrazid- hydrazones,cyclo condensation, mercapto acetic acid, 1,3-thiazolidin-4-ones, isoxazolyl-1,3-thiazolidin-4-ones