alexa Abstract | Synthesis and crystal structure studies of amino derivatives of 4-chlorophenacyl benzoate

Journal of Chemical and Pharmaceutical Research
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Abstract

Phenacyl benzoates attract commercial importance due to their various applications in the field of synthetic and photo-chemistry. They play vital role as protecting groups for carboxylic acids in organic synthesis. These are also the photosensitive blocking groups with the ease of cleaving under mild conditions. Amino derivatives of 4- chlorophenacyl benzoate (2a-c) are synthesized by reacting 4-chlorophenacyl bromide with ortho-, meta- and paraamino substituted benzoic acids separately using a slight excess of potassium carbonate in N,N-dimethyformamide medium at room temperature. These reactions offered convenience, mild conditions, high purity and good yield

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Author(s): C S Chidan Kumar Chin Wei Ooi R Venkatachalapathy Siddegowda Chandraju Ching Kheng Quah and HoongKun Fun

Keywords

Benzoates, synthesis, crystal structure, high yield and purity, Synthesis and crystal structure studies

 
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