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Short Communication Open Access
In the fabrication of transdermal patches the cost of the pressure sensitive adhesive (PSA), including its applications, release and prime coating, often surpasses the price of the backing many times.1 Lalla et al.2 have earlier reported the synthesis and evaluation of polyacrylate pressure sensitive adhesive, the solubility of the drug in the adhesive and the fraction of drug unionized can be important factors affecting the skin permeation rates of drugs from adhesive matrix types transdermal system. Therefore, we have synthesized a neutral PSA (PSA I) and an acidic PSA (PSA II) by the method of solution polymerization.
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Author(s): Jaidev S Tantry Ashish Babtiwale R Shrivastava