alexa Abstract | Synthesis and in vitro screening of 29, 30-dibromo-28-oxoallobetulin against parasitic protozoans, leishmania donovani and leishmania major

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access

Abstract

A simple synthesis and in vitro antileishmanial activity of 29,30-dibromo-28-oxoallobetulin against the parasitic protozoans, Leishmania donovani and Leishmania major is described. The structure of the compound is established on the basis of spectral data (IR, NMR, MS). Both the antiproliferative effect and the cell cycle progression were studied.

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Author(s): P Ghosh A Mandal S Dey C Pal

Keywords

Triterpenoid, halogen, leishmania, antiproliferative

 
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