alexa Abstract | Synthesis and Structural Elucidation of A New Series of 1-Formamidino-(NSubstitutedthioamido)-5-Substituted -2-THIO-4-Imino Biurets

American Journal of Pharmacology and Pharmacotherapeutics
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Research Article Open Access


Intraction of phenylthiocarbamide were carried out with dicyanamide to obtain N”- phenylformamidinoformamidinothiocarbamide(1b). which were further reacted with different alkyl/arylisothiocyanate in 1:1 molar ratio in acetone medium to obtain series of 1-formamidino- (n-substitutedthioamido)-5-substituted -2-thio-4-iminobiuret. (2) which may posses different pharmaceutical, industrial, medicinal, agricultural important which may be further cyclise to synthesis yet new series of 5 and 6 membered hetercyclic compounds. The structure of all these compounds were established on the basis of elemental analysis, IR and PMR spectral data. Rotective agent in the treatment of parkinsons disease along with standard anti-Parkinson agents.

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Author(s): ME Shelke


Dicyandiamide, 1, 3-Diformamidinothiocarbamide, Cyanoamidinothiocaramides,synthesis

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