alexa Abstract | Synthesis, characterization and antimicrobial activity of substituted tetrahydrothieno [2,3-c]pyridin-2-yl)urea derivatives

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

As a part of systematic investigation of synthesis, characterization and biological activity of several new substituted Tetrahydrothieno [2,3-c]pyridin-2-yl)urea derivatives. (3a-3k) have been synthesized by well known chemical reaction of one active methylene containing moiety with a carbonyl function and Sulfur powder to give 2- Aminothiophene ring system followed by derivatization of amino into urea by mixed anhydride method. The structures of all the synthesized compounds have been determined by their spectral and micro analytical data. All the synthesized products were evaluated for their antibacterial activity against Bacillus substilis, Escherichia coli. Klebsiella pneumoniae and Streptococcus aureus bacteria and antifungal activity against Aspergillus niger fungi respectively. Most of the synthesized compounds exhibited significant anti-bacterial and anti-fungal activities.

To read the full article Peer-reviewed Article PDF image

Author(s): Rushit Kalaria Manish Mittal Chetana Rajyaguru and Jatin J Upadhyay

Keywords

Sulphonamide, Thieno [2,3-c]pyridine, Urea, Sulphonamide, Arylureido, Antibacterial activity., Synthesis

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords