alexa Abstract | Synthesis, characterization and biocidal activities of some schiff base metal complexes

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access

Abstract

Some new mixed ligand complexes (1-5) of type ML'B (M(II)=Mn(II), Co(II), Ni(II), Cu(II) and Zn(II); HL'= o-vanillidene-2-aminobenzothiazole; B= 1,10-phenanthroline) and Schiff base metal complexes of types (ML 2 ") (6-10) and (M 2 L") (11-15) (HL"= o-vanillidene-2-amino-N-(2-pyridyl)-benzene sulfonamide) were synthesized and characterized by elemental analysis and spectral (IR, 1 H NMR and 13 C NMR) studies. The free ligands and their metal complexes have been screened for their in vitro biological activities against bacteria, fungi and yeast. The metal complexes show more potent activities compared with Schiff base ligands.

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Author(s): MA Neelakantan M Esakkiammal SS Mariappan J Dharmaraja T Jeyakumar

Keywords

Antibacterial activities, antifungal activities, mixed ligand complexes, o-vanillin, schiff base, spectral studies

 
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