alexa Abstract | Synthesis, characterization and biological aspects of novel azetidinone derivatives

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

The biologically effective Schiff bases N-arylidene-4-(furan-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5- carbohydrazide (2a-h) was prepared by condensation reaction of 4-(furan-2-yl)-6-methyl-2-oxo-1,2,3,4- tetrahydropyrimidine-5-carbohydrazide (1) aromatic aldehydes. Further reaction of schiff bases with triethyl amine (TEA) and 1,4-dioxane yields 4-(furan-2-yl)-6-methyl-2-oxo-N-(3-chloro-4-oxo-2-arylazetidin-1-yl)-1,2,3,4- tetrahydropyrimidine-5-carboxamide (3a-h). Characterization of Schiff bases and novel 2-azetidinone derivatives was carried out by CHN, FT-IR, NMR and LC-MS spectral analysis Also the antimicrobial activity of final compounds was examined against various microorganisms.

To read the full article Peer-reviewed Article PDF image

Author(s): Suresh P Jambu and Yogesh S Patel

Keywords

Heterocyclic compound, Arylidine derivatives, Azetidinone, Spectroscopic study, Antimicrobial activity., azetidinone

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords