alexa Abstract | Synthesis, characterization and biological studies of 2,5-substituted 1,3,4-thiadiazole carrying 1,2,3-triazole core

Journal of Chemical and Pharmaceutical Research
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A new series of amides (7a-m) from 2,5-substituted-1,3,4-thiadiazoles carrying 1,2,3-triazoles have been synthesized starting from 4-nitroaniline. The structures of these newly synthesized compounds were elucidated by elemental analysis, 1H NMR and mass spectral data. Also these compounds were evaluated for their antibacterial activity against bacteria Pseudomonas, Staphylcoccus aureus, Enterococcus, Eschericia coli and antifungal activity against Candida albicans, and antioxidant activity by DPPH radical scavenging assay method.

Author(s): Sushma Kadoor Balakrishna Kalluraya Shobhitha Shetty Mamatha Ballal and Vignesh Shetty


Thiadiazole, 1,2,3,-triazole, antibacterial, antioxidant activity, 1,3,4-thiadiazole

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