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Original Articles Open Access
Several fused heterocycles based on thiazolidinone derivatives were synthesized and characterized using physical properties, elemental analysis, IR and other spectral studies. New ligands i.e. 4-(2-furyl)-6-methyl-2-oxo- N-(3,5- diaryl-2- phenyl-3,3a- dihydro-2H- pyrazolo [3,4-d][1,3] thiazol-6(5H)-yl)-1,2,3,4-tetrahydro pyrimidine-5- carboxamide (5a-h) were synthesized by condensation reaction of thiazolidinone derivatives with phenyl hydrazine in presence of glacial acetic acid. Furthermore the antibacterial and antifungal activity of newly synthesized fused heterocyclic compounds was examined against various microbial strains.
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Author(s): Suresh P Jambu and Yogesh S Patel
Fused heterocycles, Thiazolidinone derivatives, Spectral studies, Antibacterial activity, Antifungal activity, thiazolidinone