alexa Abstract | Synthesis, characterization and pharmacological evaluation of some 1,4-dihydropyridines derivatives

Journal of Chemical and Pharmaceutical Research
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Abstract

A series of 1, 4-dihydropyridine derivatives were p repared from three compounds condensation reaction of ethylacetoacetate, aromatic aldehyde and ammonium h ydroxide. A new series of compounds (2a-f) were pre pared from compounds (1a-f) via reaction with β -naphthayl amine using the condensation method. The synthesized compounds were confirmed by IR, 1 H NMR, 13 C-NMR and Elemental analyses. The synthesized compo unds (1e-f) and (2a-f) were also screened for antimicrobial pro perties.

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Author(s): N Srinivasa Rao and K Lakshmi

Keywords

Synthesis of 1, 4-Dihydropyridines and Antimicrobial activity studies, pharmacological evaluation, 1,4-dihydropyridines

 
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