alexa Abstract | Synthesis, characterization and spectral studies of new pyrimidine compound

Journal of Chemical and Pharmaceutical Research
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A new series of some 3-{4-[6-(substituted phenyl)-2-thioxo-1,2,5,6-tetrahydro pyrimidin-4-yl] phenyl}-6-iodo-2- thioxo-2,3-dihydroquinazolin-4-one have been synthesized by reacting of 3-{4-[3-(substituted phenyl) prop-2- enoyl]phenyl}-6-iodo-2-thioxo-2,3-dihydroquinazolin-4-one (0.01M) with thiourea (0.01M) and 1g. of potassium hydroxide (KOH) in 30 ml of ethanol was refluxed for 3 hours. After syntheses compounds were characterized by chemical as well as instrumental methods. like elemental, IR and NMR. 

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Author(s): Naresh K Prajapati Rajiv M Shah and Pankaj S Patel


quinazolin-4-one, thiourea, ethanol, IR, NMR., pyrimidine

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