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Original Articles Open Access
Pyrazoles are well known five-membered nitrogen containing heterocyclic compounds possessing diverse bioactivities and are used extensively in pharmaceutical industry. Here we have used ionic liquid as a solvent which is highly efficient and environmentally friendly. We were interested in synthesizing 1,3-disubstituted pyrazoles using cinnamaldehyde as it gives complete regioselective product with only single isomers are obtained and the method gave us a excellent yields.
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Author(s): Chandrashekhar G Devkate Khandu D Warad Digambar D Gaikwad and Mohammad Idrees M Siddique
Ionic liquid, Pyrazole, N-Tosylhydrazine, pyrazoles