alexa Abstract | Synthesis of 1-deoxy-1-[(4-quinazolon-3-yl) amino/methyl-amino-d-fructose as cns active compounds.

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access


A new series of 4-quinazolone i.e. 1-deoxy-1-(alpha-substituted-3-amino/methylamino-4-quinazolono)-D-fruc tose have been synthesized by refluxing oxalate salt of 3-amino-4-quinazolone and anhydrous D-glucose, with a view to observe the effect of aldose and amines linkage on central nervous system. The compounds were tested on albino mice of both sex. Some of them showed CNS depressant effect.

Author(s): SR Nautiyal VR Agarwal DD Mukerji

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