alexa Abstract | Synthesis of 3-[4-[2,3-dihydro-2-(substituted aryl)-1, 5-benzothiazepin-4-yl] pheyl] sydnones as potential antiinflammatory agents.

Indian Journal of Pharmaceutical Sciences
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Research Paper Open Access


3-(p-Cinnamoylphenyl) sydnones (4-16) obtained by condensation of 3-(p-acetyphenyl) sydnones with aromatic aldehydes were condensed with 2-aminothiophenol to yield title compounds (17-29). These were evaluated orally for antiinflammatory and analgesic activities. Except compound 17 all were found to be inactive.

Author(s): K Satyanarayana M NA Rao

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