alexa Abstract | Synthesis of aryl substituted hydrazinothiazolyl pyrazole derivatives and evaluation of their biological activity

Journal of Chemical and Pharmaceutical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Original Articles Open Access

Abstract

A series of pyrazole derivatives containing thiazole moiety (IV a-g) are synthesized by the condensation of various indolyl chalcones with substituted 2-hydrazino thiazole. Indolyl Chalcones are obtained from indole-3- carboxaldehyde and substituted acetophenones. The structures of these compounds are confirmed by physicochemical as well as IR, 1H NMR, 13C NMR and Mass spectral means. The synthesized compounds are screened for their in-vitro antibacterial and antifungal potentials against various strains of micro-organisms. The pyrazole substituted with –NO2 group has been found to be more potent than the standard Gentamicin in the antifungal activity and moderate to good active against all the bacteria.



Author(s): A Faritha A Jamal Abdul Nasser and S Sahaya Sathish

Keywords

Thiazole, Pyrazole, Chalcones, Anti bacterial activity, hydrazinothiazolyl pyrazole

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords