alexa Abstract | Synthesis Of Nicorandil : An Antianginal Agent

Indian Journal of Pharmaceutical Sciences
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Nicorandil, N-[2-nitroxyethyl]-pyridine-3-carboxamide was synthesized by condensing nicotinoyl chloride with 2-nitroxyethylamine in presence of pyridine. 2-Nitroxyethylamine was prepared from 2- aminoethanol by a three step process. This process was less hazardous and comparatively economical than the literature reported methods.

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Author(s): V D Patil C L Viswanathan

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