alexa Abstract | Synthetic aspects for some novel pyrazolines and their evaluation as antimicrobial agent

Der Pharmacia Sinica
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Research Article Open Access

Abstract

With the persuasion to synthesize the molecules of biological interest we reported here the synthesis of pyrazolines from pyrrolidine chalcones and phenyl hydrazine under basic condition using methanol as a solvent media. These synthesized molecules were characterized by chemical and spectral analysis (IR, 1HNMR and mass) data. And the biological activities of these compounds were tested against different strains of bacteria and some of the fungi. As a result we got good to moderate activity which on further derivatization and modifications can provide us new route for the bioactive molecules.

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Author(s): S Shah N N Hanfi M Ziauddin and M A Baseer

 
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