alexa Abstract | Systemic Lupus Erythematosus Reactive Antibodies in Sudanese Psychiatric Patients

Asian Journal of Biomedical and Pharmaceutical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Background: the relationship between neuropsychiatric manifestations and systemic lupus erythematosus (SLE) reactive autoantibodies is controversial and was not investigated before in Sudanese psychiatric patients. Aim: to determine the association between psychiatric manifestations and several SLE reactive autoantibodies regardless of the presence of other SLE manifestations. Material and Methods: the study involved a test group of one hundred psychiatric patients and age/gender matched control group of one hundred apparently healthy subjects. Antinuclear antibodies (ANA), anti-double stranded DNA (anti-dsDNA) antibodies and ANA profile3 concentrations were measured for each studied subject using ELISA method. The association between various SLE reactive antibodies and psychiatric illnesses were assessed using Mid-P extract test. P < 0.05 was considered significant. Results: all subjects in the control group were ANA and dsDNA negative, however, only one (1%) was positive for anti-histone antibody (ANA profile3). Regarding patients with psychiatric diseases, 6% were ANA positive, 2% were dsDNA and 6% ANA profile3 positive. In contrast to dsDNA, there were significant associations between psychiatric diseases and ANA and/or ANA profile3 antibodies (P = 0.007 for ANA, P = 0.0.125 for dsDNA and P = 0.033 for ANA profile3). Conclusion: Sudanese patients with psychiatric diseases tend to have positive SLE reactive autoantibodies especially for ANA and ANA profile3 antibodies.

To read the full article Peer-reviewed Article PDF image

Author(s): Ezeldine K Alturabi Ahmed K Bolad AbdelRahman Tambal Alryah Ali Husham Elzein Altayeb Ahmed Omer Banga Souliman Ali Mohamed F Lutfi

Keywords

ANA, anti-dsDNA, ANA profile3, autoantibodies, neuropsychiatric, SLE.

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords