alexa Abstract | The Effect of Pain and Morphine Use on Complication Rates after Acute Myocardial Infarction

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Background: Patients with acute myocardial infarction usually presented to emergency department complaining from severe chest pain. This pain resulted from imbalance between oxygen supply and demand leading to serious complication. Different guidelines recommended the use of morphine as a drug of choice for this pain.

Objective: The purpose of this study was to check the effect of pain and morphine use on complication rate after acute myocardial infarction.

Methods: A cross-sectional design was used to meet the purpose of this study. Data were extracted from the medical records of 371 patients with diagnosis of acute myocardial infarction from four different hospitals in Amman, Jordan by trained cardiovascular research assistants.

Results: Patients with severe chest pain have more complications (1.65 ± 1.04 vs. 0.16 ± 1.14, p < .001) and longer length of stay in the intensive care units (5.98 ± 6.13 vs. 4.17 ± 6.99, p < .05) and in the hospital (7.34 ± 14.49 vs. 3.37 ± 3.04, p < .001) compared to patients with mild and moderate pain. The use of morphine did not have any protective effect against the development of complications or length of stay.

Conclusion: Pain increased complications and length of stay after acute myocardial infarction. Morphine use did not have a protective effect on these complications. Different treatment strategies (i.e. treating the cause) are highly recommended. Randomized control trials to check the effect of morphine use in patients with acute myocardial infarction is warranted

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Author(s): Mohannad Eid AbuRuz


Pain, Morphine, Acute myocardial infarction, Complications, Personal Health

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