alexa Abstract | The effects of titanium dioxide nanoparticles on thyroid hormones in mice

Journal of Chemical and Pharmaceutical Research
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Abstract

Nanoparticles have interactions with biological com ponents and thereby affect thyroid gland. The goal of this research was studying the effects of titanium dioxi de nanoparticles on thyroid performance. Forty matu re Syrian mice were divided in four groups. Control group, pl acebo group received only standard food and water w hereas experimental groups received 10 and 100 ppm of tita nium dioxide in water also. After 14 days, blood sa mples were taken and thyroid hormones were measured. Results showed significant reduction in T 4 and TSH amount of all groups which confirm that titanium dioxide is a str ong controller of thyroid hormones and induces hypo thyroidism.

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Author(s): Yoosefi Mahdieh Sadri Sadra Bahrami Ali Ansaripour Mohammad Taheri Melika Bahonar Mohammad Sajad and Modaresi Mehrdad

Keywords

titanium dioxide nanoparticles, TSH, T4, T3, titanium dioxide, nanoparticles, thyroid hormones

 
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