alexa Abstract | The Interaction between Epigenetics, Muscle and Cardio Vascular Diseases

Journal of Clinical Epigenetics
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Review Article Open Access

Abstract

The INTERHEART and the INTERSTROKE studies identified a number of modifiable risk factors (smoking, diabetes, dietary patterns, physical activity, etc.) that are associated with the presence of cardiovascular disease (CVD). Recent international studies have shown that lower handgrip (HG) strength is associated with an increased risk of CVD death and total mortality both in initially healthy adults and in patients with diabetes mellitus type 2 (T2DM). Furthermore, in young people from diverse populations, lower HG strength is associated with a poor cardiometabolic risk profile. Low birth weight (LBW) is associated with lower HG strength across the life-cycle and with faster infant growth, abdominal fat accumulation, higher blood pressure during adolescence, and an increased risk of cardio-metabolic diseases in the adulthood. Significant differences has been observed in HG strength of people from high, medium and low-income countries, suggesting that developmental plasticity and alterations in muscular mass resulting from altered environmental conditions during early life may also have a mediating role in the risk of cardio-vascular disease (CVD). In the present review we discuss the importance of epigenetic and its correlation to the development of muscular tissue in relation to the predictive value of strength in CVD risk and mortality. In addition, we examine with greater detail the influence of maternal undernutrition and the possible epigenetic mechanisms by which it increases the risk of CVD risk later in life.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Patricio Lopez Jaramillo Silvia Gonzalez Gomez Lazaro Vanstrahlen Gonzales Diego ZarateBernal Karina DiStefano Paul Camacho Lopez and Daniel Cohen

Keywords

Epigenetics, Handgrip, Strength, Diabetes mellitus type 2, Cardiovascular disease, Muscle mass, Nutritional Epigenetics, Epigenetic Therapy and Clinical trials, Epigenome, Environmental Epigenetics, Cardiovascular Epigenetics, Cancer Epigenetics and Diagnostics.

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords