alexa Abstract | The Prevalence and Antimicrobial Susceptibility pattern of Bacterial Uropathogens Isolated from pregnant women

European Journal of Experimental Biology
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Research Article Open Access

Abstract

A cross-sectional study was conducted on a total of 200 pregnant women to determine the prevalence and antimicrobial susceptibility of bacterial uropathogens from January to May, 2011 at Gondar University Hospital antenatal clinic, Northwest Ethiopia. Clean catch mid-stream urine specimens were collected from each study subjects. Urine culture, identification and sensitivity tests were done using standard microbiologic procedure. In this study, the overall prevalence of urinary tract infection was 12%. Of this bacteriological screening of midstream urine specimens showed that 10.2% and 15.9%, had significant bacteriuria in asymptomatic and symptomatic group respectively. Prevalence of urinary tract infection was a statistically significant association with previous history of catheterization and urinary tract infection (p<0.05). Escherichia coli was the most frequently isolated organism (41.5%) followed by coagulase negative staphylococcus (25%). Gram negative and positive bacteria accounted for (58.3%) and (41.7%) respectively. Rate of susceptibility for all isolated bacteria showed, ceftriaxon and gentamicin (87.5%) for each, amoxicillin–clavulanic acid (83.3%), ciprofloxacine (75%), and norfloxacilin (70.8%). However, most resistance was to ampicillin (91.7%), amoxicillin (79.2%), tetracycline (58.3%), cotrimoxazol (50%), and chloramphinicol (33.3%). Multi drug resistance (resistance two or more drugs) of 91.7% (22/24) was observed among the isolated bacterial uropathogens

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Author(s): Getachew Ferede Gizachew Yismaw Yitayih Wondimeneh Zufan Sisay

Keywords

UTIs, pregnant women, bacteriuria, antimicrobial drug resistance

 
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