alexa Abstract | The Role of Uric Acid in Predicting Preeclampsia Women

Journal of Chemical and Pharmaceutical Research
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Abstract

Preeclampsia is a clinical disorder that occurs only during pregnancy and the postpartum period, it affects approximately 5-8% of all pregnancies worldwide and it is characterized by high blood pressure and the presence of protein in the urine. Uric acid levels have been used for early diagnosis of preeclampsia. Hyperuricemia is one of the earliest and most consistent observations noted in preeclamptic pregnancies. severity of preeclampsia increases with increasing uric acid. The present study was done to investigate the level of uric acid in serum of preeclampsia pregnancy woman and to predict the severity of preeclampsia. The study involves 30 cases of preeclampsia of age group between 20-42 years with mean ± SD of (32.7 ± 6.2) years and 30 of healthy pregnant women of age group between 19-41 years with mean± SD of (31.1 ± 6.2). Serum uric acid was determined from all subjects by an enzymatic method (uricase). The observed mean serum uric acid levels in preeclampsia was 7.68 ± 0.79 mg/dl as compare to 4.18± 1.17 mg/dl in control group. The difference between them is significant because pvalue is less than 0.05. Routine estimation of serum uric acid level may be useful as diagnostic marker to predict the severity of preeclampsia.

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Author(s): Zubaidah Falih Mezaal AL Zuabidi

Keywords

Preeclampsia, Uric acid, Blood Pressure, Proteinuria, Severe preeclampsia, Preeclampsia

 
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