alexa Abstract | The Surface Potential Variation of Neural Stem/Progenitor Cells during Differentiation Process

Journal of Neurology and Neuroscience
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access

Abstract

Background: Stem cells have been extensively found in different tissues and organs. Understanding the characteristics of stem cells to maintain their stability may lead to find new ways to control stem cell differentiation.

Methods: In this study, the surface potential variation of neural stem/ progenitor cells (NSPCs) during differentiation process was examined. Using cell electrophoresis for measuring the electrophoretic mobility of NSPCs, we showed the electrophoretic mobility of NSPCs could rapidly increase during the first hour of differentiation process. Moreover, an activation energy model describing the variation of the surface potential of NSPCs was proposed.

Findings: When NSPCs need to change their phenotypes to differentiate, they require enough energy to process this phenotype alteration. Thus, NSPC differentiation could be enhanced or delayed by controlling electrophoretic mobility of cells, which provided a new vision for stem cell differentiation.

Conclusions: This study provided an alternative to regulate the NSPC differentiation by controlling the cellular electrophoretic mobility.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Ya Shuan Chou Jui Nan Lu Yi Chen Li Jyh Horng Wang and Tai Horng Young

Keywords

Neural stem/progenitor cells (NSPCs), Differentiation, Cell electrophoresis, Surface potential, Activation energy, Functional Neurology,Affective Neurology

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords