700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ ReadersThis Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Review Article Open Access
Daunorubicin (or daunomycin) and Doxorubicin (or adriamycin or 14-hydroxydaunomycin) are well-known anticancer agents used in cancer chemotherapy. They are anthracycline antibiotics and are commonly used in the treatment of a wide range of cancers. Doxorubicin and Daunorubicin were chemically conjugated to PEO-b-PCL (poly(ethylene oxide)-block-poly(-caprolactone)) nanoparticles. In this research, the molecular structure, Binding Energy(BE), Dipole Moment (DM), Gibbs free energy of solvation (ΔG (solvation)) and some physicochemical properties of the Doxorubicin- PEO-b-PCL and Daunorubicin- PEO-b-PCL were investigated. Our results indicate that these complexes mentioned above can be used to improve the anti-cancer activity.
To read the full article Peer-reviewed Article PDF
Author(s): S Bagheri S M Hassani and Gh Naderi
Anti-cancer drugs, Molecular geometry, Doxorubicin, Daunorubicin, PEO-b-PCL nanoparticles