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Review Article Open Access
Substituted 2-isoxazolines are well documented in the literature to possess significant biological activities. The 3,5-disubstituted and 3,4,5-trisubstituted 2-lsoxazolines have been reported to exhibit broad range of biological activities such as antimicrobial, antiinflammatory, factor Xa inhibitory, fibrinogen receptor and glycoprotein llb/llla antagonistic, anticancer, antiHIV, caspase inhibitory and as antidepressant. The present review highlights the 2-isoxazoline derivatives with potential biological activities that have been recently reported.
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Author(s): Mohd Imran S A Khan N Siddiqui