alexa Abstract | Unusual oxidation of glutathione existing the steric hindrance.

Biomedical Research
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Research on the electro-oxidation of glutathione (GSH) may give insight into its real oxidation mechanism on biomembranes. In the present work, the unusual oxidation process of GSH on an Au electrode was probed by cyclic voltammetry (CV) technique. Voltammetric studies showed that –SH in GSH was the unique target of electro-oxidation by excluding the other potential oxidation sites (amido group, carboxyl group and side-chains of glutamic acid and glycine) and the feeble influence of S–Au interaction. As a result of spatial baffle, GSH was directly oxidized to GSOxH (x = 2, 3) without forming the intermediate of glutathione disulfide (GSSG). The unusual oxidation process differs from the twostep oxidation processes of cysteine –SH on the Au electrode and the oxidation of –SH in dissolved GSH, but is similar to the biological oxidation of GSH in vivo on biomembranes, where the steric hindrance still exists.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Wansong Zong XiaoningWang Chuanxi Yang Yonggang Du Weijun Sun and Zhenzhen Xu

Keywords

Unusual oxidation, Glutathione, Cycle volt-ampere, Oxiditive damage, Steric hindrance, #

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords