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Visual Evoked Potential (VEP) is a non-invasive technique used to assess the integrity and relative state of maturation of the visual pathways in infants and children. Flash VEPs were recorded using Evoked Potential Recorder (RMS EMG. EP MARK II) with a red flash stimulus obtained from LED (Light Emitting Diode) Goggles. The present study was conducted in the Neurophysiology department on infants and children who presented with developmental delay. A total of 40 infants and children in the age group of 9 months to 10 years participated as subjects and 65 healthy age matched infants as controls were included in the study. . The data of VEP recordings was analyzed for the latency and amplitude of the first reproducible positive peak for both eyes separately. The mean and standard deviations were computed for all recordings and statistical significance was derived from unpaired student’s “t”test. There was statistically significant difference in latency and amplitude of VEPs obtained from normal infants and children and those with delayed milestones. Abnormal flash VEP findings as compared to the normative data suggest abnormal visual function in the infants and children who showed significantly delayed developmental milestones.
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Author(s): Kothari Ruchi Singh Smita Jain Manish Bokariya Pradeep Singh Ramji
Visual evoked potential, LED goggles, developmental delay