alexa Abstract | Validated spectrophotometric determination of Fenofibrate in formulation

Der Pharmacia Sinica
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


The aim of present work is to develop and validate spectrophotometric methods for the determination of fenofibrate, an anti-hyperlipidemic, fibric acid derivative in pharmaceutical formulation. Methanol was used as a solvent throughout the study. Quantitative determination of fenofibrate in pharmaceutical formulation was carried out by UV-spectrophotometric method using the absorbtivity values at 287.5 nm and by comparison with standard (method 1a and 1b) and the first order derivative absorbance values at 249.2 nm were utilized for estimation of drug (method 2). The method showed high specificity in the presence of formulation excipients and good linearity in the concentration range of 0-60 μg/mL. Percent recovery values at 287.5 nm were 100.3% while it was 100.18% at in 1st order derivative spectrophotometry at 249.2 nm (n=3). SD values showed that both spectrophotometric methods were reproducible. The intra and interday precision data demonstrated that method is precise.

To read the full article Peer-reviewed Article PDF image

Author(s): Krishna R Gupta Sonali S Askarkar Prashant R Rathod and Sudhir G Wadodkar


Fenofibrate, capsules, tablets, Derivative spectrophotometry

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us