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Review Article Open Access
The most popular route of administration for systemic action is oral route. It is probable that at least 90% of all the drugs given by oral route .There are different drug deliveries to give drug by oral route .Gastro retentive drug delivery system plays a vital role among novel drug delivery systems. The retention of oral dosage forms in the upper GIT causes prolonged contact time of drug with the GI mucosa, leading to higher bioavailability, and hence therapeutic efficacy, reduced time intervals for drug administration, potentially reduced dose size and thus improved patient compliance Therefore, extended release DDS possessing gastric retention properties may be potentially useful. In this review we summarised approaches and various perspectives of Gastro retentive drug delivery system.
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Author(s): Shaikh Siraj Molvi KhurshidI Sayyed Nazim
Gastric residence time, Gastroretentive, Floating, Mucoadhesive, Effervescent, non-effervescent