alexa Abstract | Viral Encephalitis and acute Cerebellar Ataxia Due to Late Reactivation of Varicella- Zoster Virus in an Immunocompetent Child.

Current Neurobiology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)


Reactivation of latent Varicella-Zoster virus may cause various neurological complications including meningitis, encephalitis, myelitis, vasculopathy resulting in stroke and pseudotumor cerebri. It occurs mainly in elderly or immunocompromised patients and is very rare in children. We report a 4-year and 6-months old immunocompetent boy who developed encephalitis and cerebellites, due to reactivation of latent Varicella-Zoster virus (VZV). Characteristic skin lesions of varicella were absent. Varicella-Zoster virus DNA was weakly positive in cerebrospinal fluid and serum Varicella-Zoster virus immunoglobulin G was positive while immunoglobulin M remained negative. Although rare, Varicella-Zoster virus may reactivate to cause significant central nervous system disease even in immunocompetent children. We highlight the importance of keeping a high degree of suspicion as the typical rash may not associate the disease. The key for correct diagnosis is the temporal relationship between the symptom appearance and elevated anti-VZV antibodies in serum (immunoglobulin G) or the presence of VZV DNA (PCR) in cerebrospinal fluid.

To read the full article Peer-reviewed Article PDF image

Author(s): Amal Y Kentab


Varicella-Zoster virus, Meningoencephalitis, Acute Cerebellar Ata

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version