alexa Abstract | Virulence Characters of some Methicillin Resistant Staphylococcus aureus Isolates

Archives of Clinical Microbiology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Abstract

Abstract Background: The multidrug resistance of Methicillin Resistant Staphylococcus aureus (MRSA) has become increasingly a major problem and responsible for most of the hospital acquired infections seen in local hospitals in Egypt. This emphasizes the importance of rapid detection of MRSA and investigating their virulence determinants that may be used as a target for certain anti-infectious agents that could help in the control measures in our hospitals. The aim of this study was to investigate some virulence determinants in MRSA isolates. Materials and findings: A total number of 164 bacterial isolates were recovered from different clinical specimens obtained from Ain Shams University Hospital patients (El Demerdash). Of these, 99 isolates (60.4 %) were recovered from pus, 35 isolates (21.3 %) from sputum, 18 (11 %) isolates from nasal swabs, 11 (6.7 %) isolates from blood and one isolate (0.6 %) was recovered from prostatic exudates. A total of 59 isolates were identified as S. aureus using microscopical examination, culture characteristics and biochemical reactions. Screening for methicillin resistance was done by agar disc diffusion method using cefoxitin discs. Out of the 59 S. aureus isolates, 48 ones were MRSA. Thereafter, all MRSA isolates were investigated for protease, lipase, hemolysin as well as biofilm formation. Results showed that all MRSA isolates possess protease activities while most of them did not show hemolysin or lipase activities. On the other hand, all MRSA isolates showed capability to form biofilm. The statistical analysis showed  that there was a significant increase in  mean biofilm formation among highly resistant isolates compared to those of moderate and low resistant ones (P<0.01). Conclusion:-The presence of some virulence factors in MRSA could increase their potential threats especially that most of them have multidrug resistance, rendering it difficult to treat. Further studies have to be conducted in the future targeting these virulence determinants as an additional approach that might aid in the prevention and control of such resistant organism seen in our hospitals.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Mona Hesham El gayar Mohammad Mabrouk Aboulwafa Khaled Mohammad Aboshanab Nadia Abdel haleem Hassouna

Keywords

Human Immunodeficiency Virus, Cholera

 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords